PUBLICATIONS
Peer Reviewed Publications
• Hernandez D., Cruz D., Martinez C., Garcia L., Figueroa A., Villarreal M, Manoj L., Lopez S, López-Lorenzo K., López-Juárez A., “Gender-Specific Fine Motor Skill Learning Is Impaired by Myelin-Targeted Neurofibromatosis Type 1 Gene Mutation.” Cancers 2024, 16(3):477. doi: 10.3390/cancers16030477.
• Alcalá-Zúniga D., Espinoza-Torres E., Das RK., Vargas M, Maldonado O., Benavides O, Manojkumar A, de la Garza R, Davila N, Perez I, Martinez AH, Roy D, López-Juárez A., Zarei M, Baker K, Gil M, Rodrigo H, de Erausquin GA, Roy U., “Enriched Environment Contributes to the Recovery from Neurotoxin-Induced Parkinson's Disease Pathology,” Mol Neurobiol, 2024, doi 10.1007/s12035-024-03951-w.
​
• de Blank P., Nishiyama A., Lopez-Juarez A., “A new era for myelin research in Neurofibromatosis type 1,” Glia Journal, June 2023 ahead of print, doi:10.1002/glia.24432,1–19.
​
• Reyes-Haro D., López-Juárez A., Rodríguez-Contreras A., Editorial: “Physiology and pathology of neuroglia:” Front in Cell Neurosci, 2023, 8:17:1246885. doi: 10.3389/fncel.2023.1246885.
​
• Kontaridis M. Roberts A, Schill L, Schoyer L, Stronach B, Andelfinger G, Aoki Y, Axelrad ME, Bakker A, Bennett MA, Broniscer A, Castel P, Chang CA, Cyganek L, Das TK, Hertog J, Galperin E, Garg S, Gelb BD, Gordon K, Green T, Gripp K, Itkin M, Kiuru M, Korf BR, Livingstone J, López-Juárez A, Magoulas P, Mansour S, Milner T, Parker E, Pierpont EI, Plouffe K, Rauen KA, Shankar SP, Smith S, Stevenson DA, Tartaglia M, Van R, Wagner ME, Ware S, Zenker M, The seventh international RASopathies symposium: Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery, Am J Med Genet A 2022,188(6): 1915-1927
​
• Asleh J., Shofty B., Cohen N., Kavushansky A., López-Juárez A., Constantini S., Ratner N., and Kahn I, Brain-wide structural and functional disruption in mice with oligodendrocyte specific Nf1 deletion is rescued by inhibition of NOS., PNAS, 2020. 117: 22506-22513
​
• Titus HE*, López-Juárez A.* (*equal contribution), Silbak S.H., Rizvi, T., Bogard, M., Ciraolo, G., and Ratner, N. Oligodendrocyte RasG12V expressed in its endogenous locus disrupts myelin structure through increased MAPK, nitric oxide, and notch signaling. Glia 2017, 65:1990-2002.
• López-Juárez A.*,Titus, H.E*., Silbak S.H., Pressler JW., Rizvi, T., Bogard, M., Bennett, M.R., Ciraolo, G., Williams, M.T., Vorhees, C.V., and Ratner, N. Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior. Cell Rep 2017,19:545-557.
• Klinefelter K.*, Kromme M.H.*, Bates C, Colter BT, Dailey A, Infante SK, Kania-Korwel I, Lehmler HJ, López-Juárez A, Ludwig CP, Curran CPGenetic differences in the aryl hydrocarbon receptor and CYP1A2 affect sensitivity to developmental polychlorinated biphenyl exposure in mice: relevance to studies of human neurological disorders. Mamm Genome 2017, 29:112-127
• López-Juárez A., He D, and Lu Q. R. Oligodendrocyte progenitor programming and reprogramming: Toward myelin regeneration. Brain Res 2016, 1638:209-20
​
• López-Juárez A., Howard J, Ullom K, Howard L, Grande A, Pardo A, Waclaw R, Sun YY, Yang D, Kuan CY, Campbell K, Nakafuku M. Gsx2 controls region-specific activation of neural stem cells and injury-induced neurogenesis in the adult subventricular zone. Genes Dev 2013, 27:1272-1287.
• Grande A, Sumiyoshi K, López-Juárez A., Howard J, Sakthivel B, Aronow B, Campbell K, Nakafuku M. Environmental impact on direct neuronal reprogramming in vivo in the adult brain. Nat Commun 2013, 4: 2373.
• López-Juárez A., Morales-Lazaro S, Sanchez-Sanchez R, Sunkara M, Lomeli H, Velasco I, Morris AJ, Escalante-Alcalde D. Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development. Glia 2011, 59:577-589.
• López-Juárez A., Bergmann glia receptors and transporters: possible roles in cerebellum physiology. Rev Neurol 2008, 47:527-535.
In preparation
· López-Juárez A., Titus, H.E, Pressler J.W., Rizvi, T., Williams, M.T., Vorhees, C.V., and Ratner, N., Oligodendrocyte-driven Aberrant Control of Nitric Oxide Levels is Conserved in Two RASopathy Models.
Conference Papers
• López-Juárez A., H. Titus, S. Silbak, T. Rizvi, M. Bennett, M. Williams, C. Vorhees and N. Ratner. Neurofibromin Expressed by Oligodendrocytes Regulates Myelin Structure and Behavior Through the Control of Notch signaling. XIII European Meeting on Glial Cells in Health and Disease. Edinburgh, UK. July 8-10, 2017., Glia DOI: 10.100 2 Vol 65, Issue S1, E103–E578
• Pardo AC, Howard J, Ullom K, Lopez-Juarez A, DeGraw AJ, Nakafuku M. Molecular mechanisms underlying hypoxia-induced white matter injury during early postnatal brain development. 136th Annual Meeting of the American Neurological Association, San Diego, California, September 25-27, 2011; Supplement TOC, Volume 70, Issue Supplement S15, Pages S80–S91.
• López-Juárez A., Nakafuku M., Waclaw R., Campbell K. Identity and Plasticity of Astroglial Stem Cells in Adult Neurogenic Niche. 11th European Meeting on Glial Cell Function in Health and Disease. Berlin, Germany, July 3-6, 2013. Glia. 61: S21–S22.
• López-Juárez A., Arteaga-Illan G, Ortega, A. Gaba-Induced SER-133 CREB Phosphorylation in Cultured Bergmann Glia Cells, 21st Biennial Meeting of the American Society for Neurochemistry, 2007. Conference Paper, J Neurochem, Vol 102, Issue S1, pages i–ii.
Theses
· López-Juárez A. Regulation of LPA/SP1 Signaling Through Lipid Phosphate Phosphatase 3 (LPP3) is Necessary for Correct Cerebellar Development and Motor Behavior.” National University of Mexico-Cellular and Physiology Institute,2011; Mentor: Diana Escalante-Alcalde Ph.D.
Access: http://oreon.dgbiblio.unam.mx; search: Alejandro López Juárez.
· López-Juárez A. Homolog Recombination of Bacterial Artificial Chromosomes to Study Long Distance Transcriptional Regulation of Neuronal Sodium Channel Genes.” National University of Mexico-CINVESTAV, 2004; Mentor: Refugio Garcia-Villegas Ph.D.
Access: http://oreon.dgbiblio.unam.mx; search, Alejandro López Juárez.